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“Today, more than ever, it is evident that in the fight against cancer only the synergy between all the professionals that science and technology require in supporting clinicians in the treatment path is winning

– declares the general director of the Pisana University Hospital Silvia Briani – because today genetic, biological, medical, pharmacological, physical, chemical, engineering skills are required to attack any type of tumor. One cannot do without anyone and each contributes to the success of the team. .

And therefore for us who are hospitals, but also do research, host and be protagonists of experiments and cutting-edge technologies such as the Flash project, which can translate into direct benefits for our patients, is a great opportunity and a challenge that makes us proud. M

oreover we are strengthening the sector also from the point of view of investments because 4 b unker to house heavy and high-tech machines to maximize the therapeutic offer in the area “.

“As director, I am very proud that the CNR Institute of Neuroscience is part of this initiative – explains Professor Michela Matteoli, director of the CNR Institute of Neuroscience in Pisa – unfortunately still today some highly aggressive tumors, such as brain tumors , despite extensive resection and current radiotherapy and chemotherapy treatments, inevitably recur in more than 95% of cases, with unfortunate outcomes for the patient.

The CNR Institute of Neuroscience has a long tradition of preclinical studies on various pathologies of the central nervous system, including neoplasms, with a dense network of national and international collaborations.

As part of this project, doctors Mario Costa, Enrica Strettoi and Eleonora Vannini, researchers from the Pisa office, have started collaborations with colleagues belonging to all the city realities involved and will therefore make an essential contribution to the development of preclinical models for mass a point of new generation radiotherapy treatments “.

“The National Institute of Nuclear Physics is a world leader in research in fundamental physics, in particular with particle accelerators. The technologies deriving from these sectors find important applications especially in the life sciences – specifies Dr.

Marco Grassi, director of the INFN of Pisa – INFN has therefore adhered with conviction to the project for the creation of the Pisan Center for FLASH Radiotherapy (CPFR), which is one of the research topics of priority interest for our Institute, as evidenced by the recent funding of a vast research and development program for the clinical translation of the FLASH effect.

INFN, and its Section of Pisa in particular, will participate in the research conducted at the CPFR with particular regard to the development of innovative instrumentation for the dosimetry of FLASH beams.

very high dose per pulse, and of treatment plans based on Monte Carlo methods experimental activities will collaborate with the highly specialized staff of our INFN Section and will take advantage of state-of-the-art facilities in high technologies and scientific computing “.

The task of following the various stages of implementation of the research initiative, verifying its good performance, is entrusted to a Control Committee which includes Professor Arnaldo Stefanini, expert in medical physics, Professor Fabio Beltram, president of the Pisana Foundation for Science and expert in nanoparticle physics and Professor Pierfranco Conte of the University of Padua, internationally renowned oncologist.


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